Digoxin calculator

Author: b | 2025-04-23

Tag: digoxin calculator. Calculators. Digoxin unit converter calculator. Posted on by Anna. The digoxin unit converter calculator was developed for patients Tag: digoxin unit calculator. Calculators. Digoxin unit converter calculator. Posted on by Anna. The digoxin unit converter calculator was developed for patients

Digoxin Dosing Calculator Predict Digoxin Toxicity And

Digoxin calculator to determine the optimal maintenance dose of digoxin for both heart failure and atrial fibrillation patients, based on the Bauman-DiDomenico and Koup-Jusko methods. Advanced aminoglycoside pharmacokinetic calculator. Includes a variety of dosing strategies and calulation methods to determine an optimal gentamicin, tobramycin, or amikacin dose. Advanced vancomycin pharmacokinetic calculator. Includes a variety of dosing strategies and calulation methods, including Bayesian modeling, to determine the optimal vancomycin dose. Online calculator to convert equivalent doses of corticosteroid compounds. Total phenytoin correction calculator converts a measured total phenytoin level to a corrected total and estimated free level. This calculator accounts for renal dysfunction, serum albumin level, age, and comorbidities. Total parenteral nutrition (TPN) calculator to determine a patient's macronutrient requirements (dextrose, protein, and lipids) GIR (glucose infusion rate) calculator for total parenteral nutrition (TPN) Online calculator to convert equianalgesic doses of opioid narcotic analgesics. Calculator to determine the minimum number of subjects to enroll in a study for adequate power. Calculator to determine the post-hoc power of an existing study. Printable extended-interval aminoglycoside nomograms. HAS-BLED calculator for evaluating major bleeding risk in patients with atrial fibrillation. Calculator to estimate enteral nutrition (tube feeding) needs in adults patients. Summarized landmark critical care trials -- right at your fingertips! Tool to convert OR (odds ratio) to RR (risk ratio) from logistic regression. Calculator to analyze a patient's enteral and parenteral nutrition intake, including calories, dextrose, protein, and lipids. Conversion tool to calculate benzodiazepine equivalents (convert equivalent benzodiazepine doses). Visually analyze the 10-year ACC/AHA

Digoxin Calculator for Heart Failure and Atrial Fibrillation - Digoxin

OverviewIt is important for healthcare professionals including doctors, nurses, pharmacists, and pharmacy technicians to know which medications to prescribe and at what dose to prescribe them.Dose calculations should be performed before a medication is prescribed so that it is not wasted.A dosage calculator should be used if there is any concern about the correct dose.Common means of administering a medication:Volume infusion: medication given over a set period of timeBolus: medication administered quickly or in a short burstContinuous infusion: medication administered continuously over an extended period of timeDosage regimen is a plan for the administration of a drug for a given time period to achieve the desired physiological and pharmacological effects.Loading dose is a specific dose of the medication given, usually when initiating therapy, to achieve the desired plasma Plasma The residual portion of blood that is left after removal of blood cells by centrifugation without prior blood coagulation. Transfusion Products drug concentration rapidly.Maintenance dose is the amount of medication given, usually repeatedly and at set intervals, to maintain a specific plasma Plasma The residual portion of blood that is left after removal of blood cells by centrifugation without prior blood coagulation. Transfusion Products drug concentration over a given time period.Related videosTherapeutic WindowDefinitionTherapeutic window is the dosage range within which the drug is effective (i.e., the dose at which the drug produces the desired effect) without causing toxicity.Minimum effective concentration is the minimum drug level in the blood required to achieve the desired effect.Minimum toxic concentration is the minimum drug level in the blood at which toxic side effects occur.Therapeutic indexTherapeutic index is a measure similar to therapeutic window and is used for:Measurement of the relative safety of a medicationComparison between the dose needed for therapeutic effect and the dose that causes toxicityTherapeutic index is calculated by dividing the toxic dose for 50% of the population by the minimum effective dose for 50% of the population.$$Therapeutic~index=\frac{TD_{50}}{ED_{50}}$$TD50 = toxic dose for 50% of the populationED50 = effective dose for 50% of the populationExampleThe therapeutic window for digoxin Digoxin A cardiotonic glycoside obtained mainly from digitalis lanata; it consists of three sugars and the aglycone digoxigenin. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in atrial fibrillation and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic

Digoxin Calculator – Mobile At Illinois

Initially and one quarter of the initial dose in each of 2 subsequent doses at 6–12 hr intervals. Maintenance dose: 5–10 mcg/kg given daily in 2 divided doses.PO (Children 2–5 yr): Loading dose: 30–40 mcg/kg given as 50% of the dose initially and one quarter of the initial dose in each of 2 subsequent doses at 6–12 hr intervals. Maintenance dose: 7.5–10 mcg/kg given daily in 2 divided doses.PO (Children 1–24 mo): Loading dose: 35–60 mcg/kg given as 50% of the dose initially and one quarter of the initial dose in each of 2 subsequent doses at 6–12 hr intervals. Maintenance dose: 10–15 mcg/kg given daily in 2 divided doses.PO (Infants –full term): Loading dose: 25–35 mcg/kg given as 50% of the dose initially and one quarter of the initial dose in each of 2 subsequent doses at 6–12 hr intervals. Maintenance dose: 6–10 mcg/kg given daily in 2 divided doses.PO (Infants –premature): Loading dose: 20–30 mcg/kg given as 50% of the dose initially and one quarter of the initial dose in each of 2 subsequent doses at 6–12 hr intervals. Maintenance dose: 5–7.5 mcg/kg given daily in 2 divided doses.Availability (generic available)Tablets: 0.0625 mg, 0.125 mg, 0.25 mg Oral solution (lime flavor): 50 mcg/mL Solution for injection: 0.25 mg/mL Solution for injection (pediatric): 0.1 mg/mLAssessmentMonitor apical pulse for 1 full min before administering. Hold dose and notify health care professional if pulse rate is Pedi: Heart rate varies in children depending on age; ask health care professional to specify at what heart rates digoxin should be withheld.Monitor BP periodically in patients receiving IV digoxin.Monitor ECG during IV administration and 6 hr after each dose. Notify health care professional if bradycardia or new arrhythmias occur.Observe IV site for redness or infiltration; extravasation can lead to tissue irritation and sloughing.Monitor intake and output ratios and daily weights. Assess for peripheral edema, and auscultate lungs for rales/crackles during therapy.Before administering initial loading dose, determine whether patient has taken any digoxin in the preceding 2–3 wk.Lab Test Considerations: Evaluate serum electrolyte levels (especially potassium, magnesium, and calcium) and renal and hepatic function periodically during therapy. Notify health care professional before giving dose if patient is hypokalemic. Hypokalemia, hypomagnesemia, or hypercalcemia may make the patient more susceptible to digitalis toxicity. Pedi: Neonates may have falsely elevated serum digoxin concentrations due to a naturally occurring substance chemically similar to digoxin.Toxicity and Overdose: Therapeutic serum digoxin concentrations range from 0.5–2 ng/mL. Serum levels may be drawn 6–8 hr after a dose is administered; usually drawn immediately before the next dose. Geri: Older adults are at increased risk for toxic effects of digoxin (on Beers list) due to age-related decreased renal clearance; may exist even when serum. Tag: digoxin calculator. Calculators. Digoxin unit converter calculator. Posted on by Anna. The digoxin unit converter calculator was developed for patients Tag: digoxin unit calculator. Calculators. Digoxin unit converter calculator. Posted on by Anna. The digoxin unit converter calculator was developed for patients

Digoxin Calculator Mobile At Illinois

Creatinine is normal. Digoxin requirements in older adult may change and a formerly therapeutic dose can become toxic.Observe for signs and symptoms of toxicity. In adults and older children, first symptoms of toxicity usually include abdominal pain, anorexia, nausea, vomiting, visual disturbances, bradycardia, and other arrhythmias. In infants and small children, first signs of overdose are usually cardiac arrhythmias. If these appear, withhold drug and notify health care professional immediately.If signs of toxicity occur and are not severe, discontinuation of digoxin may be all that is required.Correct electrolyte abnormalities, thyroid dysfunction, and concomitant medications. Administer potassium to maintain serum potassium between 4.0 and 5.5 mEq/L. Monitor ECG for evidence of potassium toxicity (peaked T waves).Treatment of life-threatening arrhythmias may include administration of digoxin immune Fab (Digibind) , which binds to the digitalis glycoside molecule in the blood and is excreted by the kidneys.ImplementationDo not confuse Lanoxin with levothyroxine or naloxone.High Alert: Digoxin has a narrow therapeutic range. Medication errors associated with digoxin include miscalculation of pediatric doses and insufficient monitoring of digoxin levels.For rapid digitalization, initial dose is higher than maintenance dose; 50% of total digitalizing dose is given initially. Administer remainder of dose in 25% increments at 4–8 hr intervals.When changing from parenteral to oral dose forms, dose adjustments may be necessary because of pharmacokinetic variations in percentage of digoxin absorbed: 100 mcg (0.1 mg) digoxin injection = 125 mcg (0.125 mg) tablet or 125 mcg (0.125 mg) of elixir.PO Administer oral preparations consistently with regard to meals. Tablets can be crushed and administered with food or fluids if patient has difficulty swallowing. Use calibrated measuring device for elixir; calibrated dropper is not accurate for doses of less than 0.2 mL or 10 mcg.IM Administer deep into gluteal muscle and massage well to reduce painful local reactions. Do not administer more than 2 mL of digoxin in each IM site. IM administration is not generally recommended.IV AdministrationIV Push: Dilution: May be administered undiluted. May also dilute 1 mL of digoxin in 4 mL of sterile water for injection, D5W, or 0.9% NaCl. Less diluent will cause precipitation. Use diluted solution immediately.Rate: Administer over at least 5 min.Y-Site Compatibility: acycloviralemtuzumabamikacinMORE...aminocaproic acidaminophyllineamphotericin B lipid complexanidulafunginargatrobanarsenic trioxideascorbic acidatracuriumatropineazathioprineazithromycinaztreonambenztropinebivalirudinbleomycinbumetanidebuprenorphinebutorphanolcalcium chloridecalcium gluconatecangrelorcarboplatincarmustinecefazolincefotaximecefotetancefoxitinceftarolineceftazidimeceftobiproleceftolozane/tazobactamceftriaxonecefuroximechloramphenicolchlorothiazidechlorpromazineciprofloxacincisatracuriumcisplatinclindamycincyanocobalamincyclophosphamidecyclosporinecytarabinedacarbazinedactinomycindaptomycindaunorubicindexamethasonedexmedetomidinedexrazoxanediltiazemdimenhydrinatediphenhydraminedobutaminedocetaxeldopaminedoxorubicin liposomaldoxycyclineenalaprilatephedrineepinephrineepirubicinepoetin alfaeptifibatideertapenemerythromycinesmololetoposideetoposide phosphatefamotidinefentanylfludarabinefluorouracilfolic acidfosphenytoinfurosemideganciclovirgemcitabinegentamicinglycopyrrolategranisetronheparinhetastarchhydrocortisonehydromorphoneifosfamideimipenem/cilastatinimipenem/cilastatin/relebactamindomethacinirinotecanisavuconazoniumisoproterenolketamineketorolaclabetalolLRleucovorin calciumlevofloxacinlidocainelinezolidlorazepammagnesium sulfatemannitolmeperidinemeropenemmeropenem/vaborbactammesnamethadonemethohexitalmethotrexatemethylprednisolonemetoclopramidemetoprololmetronidazolemidazolammilrinonemitomycinmorphinemoxifloxacinmultivitaminsmycophenolatenafcillinnalbuphinenaloxonenicardipinenitroglycerinnitroprussidenorepinephrineoctreotideondansetronoxacillinoxaliplatinoxytocinpalonosetronpamidronatepantoprazolepapaverinepemetrexedpenicillin Gpentobarbitalphenobarbitalphentolaminephenylephrinephytonadionepiperacillin/tazobactamplazomicinpotassium acetatepotassium chlorideprocainamideprochlorperazinepromethazinepropranololprotaminepyridoxineremifentanilrituximabrocuroniumsodium acetatesodium bicarbonatestreptomycinsuccinylcholinesufentanilsulbactam/durlobactamtacrolimustedizolidtheophyllinethiaminethiotepatigecyclinetirofibantobramycintrastuzumabvancomycinvasopressinvecuroniumverapamilvinblastinevincristinevinorelbinevoriconazolezoledronic acidY-Site Incompatibility: amiodaroneamphotericin B deoxycholateamphotericin B liposomalMORE...caspofungindantrolenediazepamdoxorubicin hydrochloridefoscarnetgemtuzumab ozogamicinidarubicinminocyclinemitoxantronepaclitaxelpentamidinephenytoinpropofoltelavancintopotecantrimethoprim/sulfamethoxazolePatient/Family TeachingInstruct patient to take medication as directed, at same time each day. Teach parents or caregivers of infants and children how to accurately measure medication. Take missed doses within 12 hr of scheduled dose or omit. Do not double doses. Consult health care professional if doses for 2 or more days are missed. Do not discontinue medication without consulting health care professional.Teach

What is buy Digoxin, Digoxin calculator - Food and Drinks - Konnect

Patient to take pulse and to contact health care professional before taking medication if pulse rate is 100.Pedi: Teach parents or caregivers that changes in heart rate, especially bradycardia, are among the first signs of digoxin toxicity in infants and children. Instruct parents or caregivers in apical heart rate assessment and ask them to notify health care professional if heart rate is outside of range set by health care professional before administering the next scheduled dose.Review signs and symptoms of digoxin toxicity with patient and family. Advise patient to notify health care professional immediately if these or symptoms of HF occur. Inform patient that these symptoms may be mistaken for those of colds or flu.Instruct patient to keep digoxin tablets in their original container and not to mix in pill boxes with other medications; may look similar to and may be mistaken for other medications.Advise patient that sharing of this medication can be dangerous.Instruct patient to notify health care professional of all Rx or OTC medications, vitamins, or herbal products being taken and to consult health care professional before taking other Rx, OTC, or herbal products, especially St. John's wort. Advise patient to avoid taking antacids or antidiarrheals within 2 hr of digoxin.Advise patient to notify health care professional of this medication regimen before treatment.Patients taking digoxin should carry identification describing disease process and medication regimen at all times. Geri: Review fall prevention strategies with older adults and their families.Rep: Advise females of reproductive potential to notify health care professional if pregnancy is planned or suspected, may increase risk for low birth weight or preterm birth. Digoxin is recommended as a first-line agent for chronic treatment of highly symptomatic supraventricular tachycardia in pregnancy. Monitor for maternal arrhythmias during labor and delivery. Monitor maternal serum digoxin concentrations; may require dose adjustments during pregnancy and postpartum; may lead to ↑ risk of arrhythmias during labor and delivery. Monitor neonates for signs and symptoms of digoxin toxicity (vomiting, cardiac arrhythmias). Monitor neonates for signs/symptoms of digoxin toxicity.Emphasize the importance of routine follow-up exams to determine effectiveness and to monitor for toxicity.Evaluation/Desired OutcomesDecrease in severity of HF.Increase in cardiac output.Decrease in ventricular response in atrial fibrillation or atrial flutter.Termination of paroxysmal atrial tachycardia.

Digoxin Calculator for Heart Failure and Atrial

GeneralHigh Alert Medication: This medication bears a heightened risk of causing significant patient harm when it is used in error. **BEERS Drug**Pronunciation: di-jox-inTrade Name(s)LanoxinTher. Class.antiarrhythmicsinotropicsPharm. Class.digitalis glycosidesIndicationsHF.Atrial fibrillation and atrial flutter (slows ventricular rate).Paroxysmal atrial tachycardia.ActionIncreases the force of myocardial contraction.Prolongs refractory period of the AV node.Decreases conduction through the SA and AV nodes.Therapeutic Effect(s): Increased cardiac output (positive inotropic effect) and slowing of the heart rate (negative chronotropic effect).PharmacokineticsAbsorption: 60–80% absorbed after oral administration of tablets; 70–85% absorbed after administration of elixir; 80% absorbed from IM sites (IM route not recommended due to pain/irritation). IV administration results in complete bioavailability.Distribution: Widely distributed to tissues.Metabolism and Excretion: Excreted almost entirely unchanged by the kidneys.Half-life: 36–48 hr (↑ in renal impairment).TIME/ACTION PROFILE (antiarrhythmic or inotropic effects, provided that a loading dose has been given)ROUTEONSETPEAKDURATIONPO30–120 min2–8 hr2–4 days†IM 30 min4–6 hr2–4 days†IV5–30 min1–4 hr2–4 days††Duration listed is that for normal renal function; in impaired renal function, duration will be longer.Contraindication/PrecautionsContraindicated in: Hypersensitivity;Uncontrolled ventricular arrhythmias;Heart block (in absence of pacemaker);Idiopathic hypertrophic subaortic stenosis;Constrictive pericarditis;Known alcohol intolerance (elixir only).Use Cautiously in: Hypokalemia (↑ risk of digoxin toxicity);Hypercalcemia (↑ risk of toxicity, especially with mild hypokalemia);Hypomagnesemia (↑ risk of digoxin toxicity);Diuretic use (may cause electrolyte abnormalities including hypokalemia and hypomagnesemia);Hypothyroidism;MI;Renal impairment (↓ dose);Obesity (base dose on ideal body weight);OB: Monitor neonates for signs/symptoms of digoxin toxicity; monitor levels in mother during pregnancy as levels may fluctuate during pregnancy and postpartum periods; may lead to ↑ risk of arrhythmias during labor and delivery;Lactation: Use with caution while breastfeeding; Geri: Appears on Beers list. Avoid use as first-line therapy for rate control in atrial fibrillation or for HF in older adults; if used, avoid using dose >0.125 mg/day.Adverse Reactions/Side EffectsCV: bradycardia, ARRHYTHMIAS, ECG changes, heart blockEENT: blurred vision, yellow or green visionGI: anorexia, nausea, vomiting, diarrheaHemat: thrombocytopeniaNeuro: fatigue, headache, weakness.* CAPITALS indicate life-threatening.Underline indicate most frequent.InteractionsDrug-Drug Thiazide and loop diuretics, piperacillin/tazobactam, amphotericin B, corticosteroids, and excessive use of laxatives may cause hypokalemia, which may ↑ risk of toxicity. Quinidine and ritonavir may ↑ levels and lead to toxicity; ↓ digoxin dose by 30–50%. Amiodarone and dronedarone may ↑ levels and lead to toxicity; ↓ digoxin dose by 50%. Cyclosporine, itraconazole, mirabegron, propafenone, quinine, spironolactone, and verapamil may ↑ levels and lead to toxicity; serum level monitoring/dose ↓ may be required.Levels may be ↓ by some antineoplastics (bleomycin, carmustine, cyclophosphamide, cytarabine, doxorubicin, methotrexate, procarbazine, vincristine ), activated charcoal, cholestyramine, colestipol, metoclopramide, penicillamine, rifampin, or sulfasalazine.In a small percentage (10%) of patients, gut bacteria metabolize digoxin to inactive compounds macrolide anti-infectives (erythromycin, azithromycin, clarithromycin ) and tetracyclines, by killing these bacteria, will cause ↑ levels and toxicity; dose may need to be ↓ for up to 9 wk.Additive bradycardia. Tag: digoxin calculator. Calculators. Digoxin unit converter calculator. Posted on by Anna. The digoxin unit converter calculator was developed for patients